Stavros Thomopoulos email: ThomopoulosS@wustl.edu 812 Yalem Research Building Phone: +1 (314) 362-8605 FAX: +1 (314) 362-0334 Department of Orthopaedic Surgery Washington University Campus Box 8233 St. Louis, MO 63130

  Stavros Thomopoulos
  Assistant Professor of Orthopaedic Surgery (Joined 2003) and Biomedical Engineering (Joined 2006)

• Ph.D., Biomedical Engineering, University of Michigan, 2001
• M.S., Biomedical Engineering, University of Michigan, 1998
• M.S., Mechanical Engineering, University of Michigan, 1997
• B.S., Mechanical Engineering, Columbia University, 1995

 Research Interests:

• Tissue engineering
  • Structure-function relationships in engineered collagen constructs
  • The role of the physical environement on tissue formation in vitro
  
  
  
• The tendon-to-bone insertion site
  • The role of the physical environment on the development of the tendon-to-bone insertion
  • Properties of the natural tendon-to-bone insertion site
  • Properties of the healing tendon-to-bone insertion site
  • Treatments for tendon-to-bone injuries (e.g., regulation of the loading environment, application of growth factors, inhibition of growth factors)
  
  
  

  Representative Publications:

• Galatz LM, Sandell LJ, Rothermich SY, Das R, Mastny A, Havlioglu N, Silva M, Thomopoulos S. " Characteristics of the rat supraspinatus tendon during tendon to bone healing after acute injury. "   Journal of Orthopaedic Research 24(3):541-550, 2006. PubMed Citation/ Full Text
  
• Thomopoulos S, Marquez JP, Weinberger B, Birman V, Genin GM. " Collagen fiber orientation at the tendon to bone insertion and its influence on stress concentrations. "   Journal of Biomechanics 39(10):1842-1851, 2006. PubMed Citation/ Full Text
  
• Thomopoulos S, Fomovsky G, Holmes JW. " The development of structural and mechanical anisotropy in fibroblast populated collagen gels. "   Journal of Biomechanical Engineering 127:742-750, 2005. PubMed Citation/ Full Text
  
• Galatz LM, Rothermich SY, Zaegel M, Silva MJ, Havlioglu N, Thomopoulos S. " Delayed repair of tendon to bone injuries leads to decreased biomechanical properties and bone loss. "   Journal of Orthopaedic Research 23:1441-7, 2005. PubMed Citation/ Full Text
  
• Thomopoulos S, Harwood FL, Silva MJ, Amiel D, Gelberman RH. " Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro. "   Journal of Hand Surgery [American]. 30(3):441-7, 2005. PubMed Citation/ Full Text
  
• Thomopoulos S, Williams GR, Gimbel JA, Favata M, Soslowsky LJ. " Variation of biomechanical, structural, and compositional properties along the tendon to bone insertion site. "   Journal of Orthopaedic Research 21(3):413-9, 2003. PubMed Citation/ Full Text
  
• Thomopoulos S, Williams GR, Soslowsky LJ. " Tendon to bone healing: differences in biomechanical, structural, and compositional properties due to a range of activity levels. "   Journal of Biomechanical Engineering 125(1):106-13, 2003. PubMed Citation/ Full Text
  

 Departmental Web Pages:

• Orthopaedics
• Biomedical Engineering